产品货号：
Z27821
中文名称：
SYPL2抗体
英文名称：
Anti-SYPL2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SYPL2 Antibody |
| 指标别名 | MG29,Synaptophysin-like protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SYPL2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SYPL2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SYPL.The immunogen is located within the last 50 amino acids of SYPL2. |
| 计算分子量 | 30kDa |
| 成分 | SYPL2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SYPL2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SYPL2,also known as Mitsugumin 29,was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family.SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle.SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR),thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function.Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores. |
| Uniprot ID | Q5VXT5 |
| 基因名全称 | Synaptophysin-like 2 |
| 蛋白名全称 | Synaptophysin-like 2 |
| 推荐稀释比 | SYPL2 antibody can be used for detection of SYPL2 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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